JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rat...
2013-08-09
SUMMARYHyperactive PI3K/mTOR signaling is prevalent in human malignancies and its inhibition has potent antitumor consequences. Unfortunately, single-agent targeted cancer therapy is usually short-...
2013-08-09
SUMMARYHyperactive PI3K/mTOR signaling is prevalent in human malignancies and its inhibition has potent antitumor consequences. Unfortunately, single-agent targeted cancer therapy is usually short-...
Suppression of miRNA-708 by Polycomb Group Promotes Metastases by Calcium...
2013-08-09
SUMMARY The progression of cancer to metastatic disease is a major cause of death. We identified miR-708 being transcriptionally repressed by polycomb repressor complex 2-induced H3K27 trimethylati...
2013-08-09
SUMMARY The progression of cancer to metastatic disease is a major cause of death. We identified miR-708 being transcriptionally repressed by polycomb repressor complex 2-induced H3K27 trimethylati...
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